Laboratory and Cryobiological Cryogenic Liquid Uses

Laboratory equipment and sensors, environmental chambers, and the storage/preservation of biological samples are frequent uses for cryogenic liquids. Liquid cryogens can rapidly reduce sample temperatures, maintain samples at very cold conditions, and create an environment to test products. Liquid nitrogen (LN2), for its versatility, and liquid helium (LHe), for its ultra-cold characteristics, make them popular cryogenic liquids used in the laboratory.

Medical facilities, both research, and commercial, commonly use cryogenic liquids for test equipment and the storage and shipment of biological samples. Magnetic Resonance Imaging (MRI) units use liquid helium to cool their ultra-powerful magnets. Liquid nitrogen is often used to store, handle, and ship biological samples, although some MRI units also utilize liquid nitrogen. Another application that many people are familiar with, if they have visited a dermatologist, is the removal of warts or diseased tissue with liquid nitrogen using a swab or cryospray device.

The major cryobiology uses for Technifab products involve the cryopreservation of cells and tissues, cryosurgery, and lyophilization. Cryogenic liquids have advantages over mechanical freezers due to their speed and ability to limit the sharp ice crystals in tissue and cells that can form with other methods.


Technifab’s vacuum jacketed products are ideal in a laboratory or cryobiological setting where reduced condensation, frost, and non-corrosiveness are valued. The added efficiency, quick cryogen delivery, performance, and cost savings are additional benefits that make our vacuum-jacketed products even more valuable in a laboratory and cryobiological settings.

Vacuum-jacketed pipe and vacuum-jacketed transfer hoses are frequently used for the delivery of liquid nitrogen and liquid helium. Technifab’s Techniguard line of rigid and bendable vacuum insulated pipe, and our Techflex hoses allow frost-free transfer of liquid cryogens that look as good as they perform. Many Original Equipment Manufacturers (OEMs) use Techniguard vacuum jacketed pipe or Techflex transfer hoses in their laboratory or equipment.

Phase separators and valves may be used in the system to ensure a more consistent and better quality liquid cryogen is delivered where and when needed.

For transferring cryogenic liquids, transfer hoses may have ‘stingers’ on one end to take liquid to or from a dewar. Charging MRI units or delivery to storage dewars, especially utilizing liquid helium, makes this a popular use. Helium’s cold temperatures and high cost have made Technifab’s Liquid Helium Equipment popular. Our hoses have proven superior performance in independent laboratory tests, resulting in lower liquid helium losses than competitors.

We’ve also released a special Techniguard vacuum-insulated pipe designed to rapidly deliver liquid nitrogen or other cryogens to the use point. Techniguard R50T and R65T pipe is ideal for cryobiological settings or freezers with intermittent liquid nitrogen use.

Our line of custom cryogenic dewars is often used in locations where small quantities of cryogens are needed or that may not have a cryogen delivery system. We also offer a biological dewar that is designed for holding biological samples. We provide dewars manufactured with the same quality and customer service as our other products. We even offer dewars online for faster delivery of these high-performance products.